Effects of cured dentin bonding materials on human monocyte viability.

OBJECTIVES Dentin Bonding Agents (DBAs) have been proposed as root-end filling materials. This study examined the effect of polymerized DBAs on human monocyte viability. STUDY DESIGN Monocytes were directly isolated from peripheral blood and being exposed to cured Scotch bond I (Single Bond) and Prime & Bond in different time intervals (36 and 72 hours). The viability of monocytes was determined by MTT assay. RESULTS Viability of the cells was time dependent. There was no significant difference between the effect of 2 DBAs on monocytes. CONCLUSION Results indicate that DBAs in polymerized form can alter the viability of monocytes and decrease it within time.